Functional Genomics and Biomarker Research
in Kidney Disease

Publications

• 
  "Laser-Capture Microdissection of Renal Tubule Cells and Linear Amplification of RNA for Microarray Profiling and Real-Time PCR"

  In press in

  Methods Mol Biol 2011

  » Pdf-version of the paper  
• 
  "Mapping of molecular pathways, biomarkers and drug targets for diabetic nephropathy"

  Published in

  » Proteomics Clin Appl. 2011 Mar 11.

  » Pre-peer-reviewed version of the paper  
• 
  "Validity of Biomarkers Predicting Onset or Progression of Nephropathy in Patients with Type 2 Diabetes: A Systematic Review"

  In press in

  Diabetic Medicine 2011

  » Revised peer-reviewed version of the paper  

  » Brief overview (figures, tables and text files)
• 
  "Linking transcriptomic and proteomic data on the level of protein interaction networks"

  Published in

  » Electrophoresis. 2010 Jun;31(11):1780-9

  » Pdf-version of the original paper  
• 
  "Up-Regulation of Versican Predicts Progression of Chronic Kidney Disease"

  Submitted

  » Learn more.. (restricted access) 
• 
  "STAT/SOCS signalling in chronic kidney disease"

  Work in Progress..
• 
  "Functional significance of changes in genome wide gene expression profiles associated with renal aging"

  Work in Progress..
• 
  "Association of renal genomic profiles with histopathology and clinical outcome"

  Under review

  » Learn more.. (restricted access) 
• 
  "Neuropilin-1 and neuropilin-2 are differentially expressed in human proteinuric nephropathies and cytokine-stimulated proximal tubular cells"

  Published in

  » Lab Invest. 2009 Sep 7. [Epub ahead of print]
• 
  "Hypoxia response and VEGF-A expression in human proximal tubular epithelial cells in stable and progressive renal disease"

  Published in

  » Lab Invest. 2009 Mar; 89(3): 337-46. Epub 2009 Jan 12

  » Brief overview (figures and tables)

  » MIAME-Checklist  

  » Summarised raw data (Excel-sheet)  
• 
  "Bortezomib-induced survival signals and genes in human proximal tubular cells"

  Published in

  » J Pharmacol Exp Ther. 2008 Dec; 327(3): 645-56. Epub 2008 Sep 5

  » Brief overview (figures and tables)

  » MIAME-Checklist  

  » Summarised raw data (Excel-sheet)  
• 
  "Biomarker candidates for cardiovascular disease and bone metabolism disorders in chronic kidney disease: a systems biology perspective"

  Published in

  » J Cell Mol Med. 2008 Aug; 12(4): 1177-87. Epub 2008 Feb 8

  » Brief overview (figures and tables)

  » Pdf-version of the original paper  
• 
  "In vitro-transcriptional response of polymorphonuclear leukocytes following contact with different antigens"

  Published in

  » Eur J Clin Invest. 2007 Nov; 37(11): 860-9. Epub 2007 Oct 11

  » Brief overview (figures and tables)

  » MIAME-Checklist  

  » Summarised raw data (Excel-sheet)  
• 
  "Gene expression profiles of human proximal tubular epithelial cells in proteinuric nephropathies"

  Published in

  » Kidney Int. 2007 Feb; 71(4): 325-35. Epub 2006 Dec 20

  » Brief overview (figures and tables)

  » Pdf-version of the original paper  

  » MIAME-Checklist  

  » Summarised raw data (Excel-sheet)  
• 
  "Reliability of t7-based mRNA linear amplification validated by gene expression analysis of human kidney cells using cDNA microarrays"

  Published in

  » Nephron Exp Nephrol. 2004; 97(3): e86-95

  » Brief overview (figures and tables)

  » Pdf-version of the original paper